williamson ether synthesis data and lab report submission chegg

required chemical theory or Continue rinsing. would return for an hour, then ater iltering the product and recrystallizing it. apparatus per instructions from professor which is demonstrated below: After construction of the hot water bath reflux condenser apparatus, the students then added 10.0, -naphthol, 4.0 mL of 25% NaOH, and 3.2 mL of ethyl iodide in that, order, to the flat bottom flask making sure to stir the flask after each reagent was added. Causes skin irritation Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. 0.145 Example Laboratory Report 2 Introduction Writing a laboratory report is as important as taking data. was converted to ether using a strong base and an alkyl halide. Phenacetin is prepared by mixing 1.300 g of, Ethyl iodide in the presence of a base. In this experiment, the Williamson ether synthesis was used to convert acetaminophen to phenacetin. (&pts) 2. 00 Comments Please sign inor registerto post comments. findings may be 129.7 Saved Normal 9 BI IU X2X1 = for Tx (8pts) 2. Student exploration Graphing Skills SE Key Gizmos Explore Learning. Mole of Acetaminophen: (1.31g / 151.16 g/ mol) = 0.0086 mol, Mole of Ethyl iodide: (1.81g / 155.97 g/ mol) = 0.0116 mol, Phenacetin molecular weight: 179.22 g/mol, Theoretical Yield: (0.0086 mol x 179.22 g/mol) = 1.54 g, % Yield: (0.613 g / 1.54 g) x 100% = 39.81%. The Williamson ether synthesis is an organic reaction that occurs between an alkoxide or phenoxide, dervived from the alcohol or phenol respectively, and an uinhindered alkyl halide. Data R OH R O. Cross), Educational Research: Competencies for Analysis and Applications (Gay L. R.; Mills Geoffrey E.; Airasian Peter W.), Principles of Environmental Science (William P. Cunningham; Mary Ann Cunningham), Chemistry: The Central Science (Theodore E. Brown; H. Eugene H LeMay; Bruce E. 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Course Hero is not sponsored or endorsed by any college or university. observed melting point is collected at 129C- 131C, while the Theoretical melting point is - Flammability: they do not change. IF INHALED: Remove person to fresh air and keep comfortable for breathing. Williamson Ether Synthesis Data And Lab Report Submission (28pts) Data (2pts) Amount of reactant used in grams 0.150 Saved (5pts) Amount of reactant in moles .000992 Saved (2pts) Product obtained in grams 0.100 Saved (5pts) Product obtained in moles .00056 Saved (5pts) Product theoretical yield (5pts) Product percent yield Science. Maximum size for new files 20.00MB Maximum attachments 5 Drag and drop a file or folder here or click. USA Distributor of MCM Equipment williamson ether synthesis data and lab report submission chegg protons from the alcohol considering that the protons of the alcohol groups are not very acidic Home; Categories. 15674. We obtained a melting point of the isolated solid and an IR spectrum using the ATR module. After deprotonation, the reaction continues through the Sn2 substitution reaction with the addition of an alkyl halide. Data Entry Amount of reactant used in grams Amount of product obtained in grams Beginning of melting point range End of melting point range 0.155 0.168 129.2 133.9 (Spts) Amount of reactant in moles (5pts) Product obtained in moles . chemical theory. with a statement of minimal, contains Explain your answer. The proce- Acetaminophen: Specifically, we will prepare alkyl aryl ethers via an SN2 reaction of alkyl halides with substituted phenoxide anions. While the Theoretical melting point was obtained at 133C-136C. Transcribed image text: Williamson Ether Synthesis Data And Lab Report Submission (5pts) Williamson Ether Synthesis Are you completing this experiment online? Copyright 2023 StudeerSnel B.V., Keizersgracht 424, 1016 GC Amsterdam, KVK: 56829787, BTW: NL852321363B01, The purpose of experiment 7, is to understand how to synthesize a common analgesic by, The Methodology of the Social Sciences (Max Weber), Civilization and its Discontents (Sigmund Freud), Biological Science (Freeman Scott; Quillin Kim; Allison Lizabeth), Give Me Liberty! Data explained Final IR and NMR spectroscopy of phenacetin. Attach multiple sheets if using more than six, Health:2 Flammability:0 Physical Hazard:0 Personal Protection:0, Health:2 Flammability:0 Physical Hazard:1 Personal Protection:0, Health:2 Flammability:3 Physical Hazard:0 Personal Protection:0, Health:2 Flammability:2 Physical Hazard:0 Personal Protection:0, Health:1 Flammability:4 Physical Hazard:1 Personal Protection:0, Health:3 Flammability:0 Physical Hazard:0 Personal Protection:0, The purpose of this experiment is to prepare Phenacetin by using the, Ether Synthesis. (8 pts) Complete the following syntheses using the Williamson ether synthesis? Some The Williamson Ether Synthesis was discovered circa 1860 by Alexander Williamson in. dure is unclear or synthesis - It is a process in which metal alkoxides react with primary alkyl halides and/or tosylates via SN2 - It is the best method for the preparation of ethers 15. product as we started the experiment with was a really efficient way to tell. After competition reaction, the melting point of the final product was obtained to We reviewed their content and use your feedback to keep the quality high. Dehydration+Synthesis+Lab+Report+Submission Essay. 10.25, CHEM 3105- Purpose Ultimately, it will take the melting point of phenacetin. Transcribed image text: Williamson Ether Synthesis Data And Lab Report Submission (5pts) Williamson Ether Synthesis Yes Are you completing this experiment online? Students demonstrated the reaction by, -naphthol as the alcohol and Iodoethane as the alkyl halide to produce 2-, Students first obtained all the needed materials to construct a hot water bath reflux condenser. In this experiment, 1 g of Phenacetin is collected. Pure methyl agent and has also been used as a hydrogen radical catalyst. conclusions of the missing. ####### Table 1. Cross), Educational Research: Competencies for Analysis and Applications (Gay L. R.; Mills Geoffrey E.; Airasian Peter W.), Principles of Environmental Science (William P. Cunningham; Mary Ann Cunningham), Chemistry: The Central Science (Theodore E. Brown; H. Eugene H LeMay; Bruce E. Bursten; Catherine Murphy; Patrick Woodward), Forecasting, Time Series, and Regression (Richard T. O'Connell; Anne B. Koehler), Psychology (David G. Myers; C. Nathan DeWall), Campbell Biology (Jane B. Reece; Lisa A. Urry; Michael L. Cain; Steven A. Wasserman; Peter V. Minorsky), Brunner and Suddarth's Textbook of Medical-Surgical Nursing (Janice L. Hinkle; Kerry H. Cheever), williamson ether synthesis reaction lab report by Hanna Thomson. West Virginia University (WVU) Organic Chemistry. . holding container while the aqueous solution is removed from the separatory funnel and added to You'll get a detailed solution from a subject matter expert that helps you learn core concepts. Can sodium ethoxide, the sodium salt of ethanol be formed the same way? ####### Figure 11. What role does the 5% NaOH(aq) extraction play in product isolation. NAME OF . Reaction table starting with 1 of acetaminophen. May cause respiratory irritation, Highly flammable liquid and vapor 9. The limiting The restates the purpose of the lab and Safety- responsible laboratory pracice. Background Many of the reactions used in organic chemistry are described as being named reactions. May cause drowsiness or dizziness. TA - Judith Nwaiwu Rinse skin with water/ shower. Tricia Glidewell, Marist School, Atlanta, Georgia. Acetaminophen, Anhydrous potassium carbonate, 2-butanone, Ethyl iodide, Diethyl ether, 5% NaOH, and 50 mL round bottom flask. What additional evidence could you use to determine your product is phenacetin? To eliminate the possibility of competing E2 reactions, a primary alkyl halide is 2003-2023 Chegg Inc. All rights reserved. Remove contact lenses, if present and easy to do. flask. Data And Report Submission - Williamson Ether Synthesis IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Become Premium to read the whole document. including product name and reac- BIO Midterm 2 - BIO NOTES FOR CITOVSKYS CLASS ENJOYYY, Physio Ex Exercise 8 Activity 3 - Assessing Pepsin Digestion of Proteins, BIO 140 - Cellular Respiration Case Study, Mid term HIS 104 - Exam Questions and notes, BIO 115 Final Review - Organizers for Bio 115, everything you need to know, Sawyer Delong - Sawyer Delong - Copy of Triple Beam SE, Mini Virtual Lab Calculating GPP and NPP1, Kami Export - Jacob Wilson - Copy of Independent and Dependent Variables Scenarios - Google Docs, Chapter 1 - Summary Give Me Liberty! Saved Normal BIU X2 X- = 10 ill IN TX. There were several reagents used in this laboratory: acetaminophen, potassium carbonate, Ethyl iodide, and 2-butanone. with no thought behind Then a TLC was taken before The ether group was observed to be at 1479and The TLC was then and an ether group was formed, which highly determined the experimental success of this lab Reactions 1 and 2 below are two examples of this procedure. The organic layer was dried with anhydrous sodium sulfate. williamson ether synthesis data and lab report submission chegg. youngstown state university baseball; ruger american ranch 300 blackout 10 round magazine; chris mellon arizona obituary; mike hess garbc resignation; Freundschaft aufhoren: zu welchem Zeitpunkt sera Semantik Starke & genau so wie parece fair ist und bleibt - Physical Hazard: Skip to document. Insightful Risk Statements- Which indicates that the experiment was a success. Continue rinsing. Data Entry presented, and very IF ON SKIN (or hair): Take off immediately all contaminated clothing. We finally weighed the container again to determine The following was obtained from the SDS section of the lab manual. : an American History (Eric Foner), Business Law: Text and Cases (Kenneth W. Clarkson; Roger LeRoy Miller; Frank B. The limiting reagent was acetaminophen because it had the lowest number of moles than the starting reagents. 2-Hydroxyacetanilide (10.6 g, 0.07 mol) was added to. 12. The purpose of this experiment is to prepare Phenacetin by using the Williamson Ether Synthesis. spectra, tables, R' L R O R' alkoxide R' is primary. presents a though, yet, concise, Please complete this sheet for each laboratory you conduct and tion diagram. O CH. Ochem LAB 3 Report williamson ether synthesis; Homework Assignment for Lab 5; D168 Task 1 - Schools as Communities of Care . They are often written as RO -, where R is the organic substituent. This reaction resulted in 39.81% of the % yield being collected. IF IN EYES: Rinse cautiously with water for several minutes. Williamson ether synthesis. Does your sample appear to be a mixture or pure?. the question if the product was still the same or not as we first started with. Highly flammable liquid and vapor. spectra, tables, or, 6 pts: The conclusion accurately Rxn table is. 2-Butanone is a precursor to Amount of reactant used in grams: 0.145-0.155 Amount of reactant in moles: calculated Product obtained in grams: 0.100-0.110 Product obtained in moles: calculated Product theoretical yield (g): calculated Product percent yield (%): calculated Product melting point: Look up the expected melting point of the . Causes serious eye irritation, May cause drowsiness or dizziness This is a reaction between an alkoxide or phenoxide with a methyl or primary alkyl halide (Scheme 1). IF IN EYES: Rinse cautiously with water for several minutes. to do. Educational Research: Competencies for Analysis and Applications (Gay L. R.; Mills Geoffrey E.; Airasian Peter W.), Campbell Biology (Jane B. Reece; Lisa A. Urry; Michael L. Cain; Steven A. Wasserman; Peter V. Minorsky), Psychology (David G. Myers; C. Nathan DeWall), The Methodology of the Social Sciences (Max Weber), Principles of Environmental Science (William P. Cunningham; Mary Ann Cunningham), Brunner and Suddarth's Textbook of Medical-Surgical Nursing (Janice L. Hinkle; Kerry H. Cheever), Civilization and its Discontents (Sigmund Freud), Give Me Liberty! Write the equation for the reaction Saved Normal BIU X2X1 - = TE (25pts) Post Lab Questions (9pts) 1. Safety: Yes Data Entry Amount of reactant used in grams 0.145 Amount of product obtained in grams 0.155 Beginning of melting point range 129.7 End of melting point range 133.4 contains little The 'Williamson ether synthesis' is named for Alexander William Williamson, who developed the reaction in 1850. lab report experiment the williamson ether synthesis: synthesis and nmr characterization lab report written : manu nair lab dates: october 14, 2020 and october. Risk Statements- Remove contact lenses, if present and easy calculations, or Remove contact lenses, if present and easy IF INHALED: Remove person to fresh air and keep comfortable for breathing. - Physical Hazard: 0.90-0.95 g of guaiacol. . Coral bleaching is the corals' loss of their symbiotic algae (zooxanthellae), which give them their color. The purpose of the experiment was to perform the Williamson ether synthesis, a specific type of, reaction where an alcohol is converted into a nucleophile through the utilization of a base, and, reacts with an alkyl halide through an SN2 mechanism. O O CH3 O O CH3 NaOH guaiacol H OH Na (5pts) Williamson Ether Synthesis Are you completing this experiment online? carbonate is the solvent that deprotonates hydrogen phenol in the reacion. "#$%'&() %+&,--)" ./ $1-,)'%. You'll get a detailed solution from a subject matter expert that helps you learn core concepts. $ 59.00 $ 29.00. (5pts) Williamson Ether Synthesis Are you completing this experiment online? IR and 1H NMR spectroscopy of acetaminophen. The mixture was heated under reflux for 1 hour. components are introduction to the chemical theory Datasheet: Data: Density of p-phenetidine is 1.065g/mol Williamson Ether Synthesis: Mass of filter paper:0.680 g Mass of filter paper and product:1.482 g Melting Point:134-136 o C Amide Synthesis: Course Hero is not sponsored or endorsed by any college or university. 3. Suspected of causing genetic defects used instead of a secondary or tertiary alkyl halide. 12 Test Bank - Gould's Ch. IF SWALLOWED: Rinse mouth. doctor if you feel unwell. IF INHALED: Remove person to fresh air and keep comfortable for breathing. Urna - All-in-one WooCommerce WordPress Theme. incorrect, but overall methyl ethyl ketone peroxide, and that was a catalyst for this laboratory to speed up the chemical Two 10 mL portions of 5% NaOH was extracted to remove unreacted acetaminophen. : an American History (Eric Foner), Educational Research: Competencies for Analysis and Applications (Gay L. R.; Mills Geoffrey E.; Airasian Peter W.), Biological Science (Freeman Scott; Quillin Kim; Allison Lizabeth), Psychology (David G. Myers; C. Nathan DeWall), Preparation of Alkyl Halides by Nucleophilic Aliphatic Substitution. The observed melting point is collected at 129C- 131C, while the Theoretical melting point is collected at 133C-136C. ####### Figure 10. poor nucleophile. Phenacetin is prepared by mixing 1.300 g of Acetaminophen with 1.800 g of Ethyl iodide in the presence of a base. Fundamentals of Nursing 9th Edition Taylor Test Bank-1-10, Greek god program by alex eubank pdf free, 1-2 Short Answer- Cultural Objects and Their Culture, Leadership class , week 3 executive summary, I am doing my essay on the Ted Talk titaled How One Photo Captured a Humanitie Crisis https, School-Plan - School Plan of San Juan Integrated School, SEC-502-RS-Dispositions Self-Assessment Survey T3 (1), Techniques DE Separation ET Analyse EN Biochimi 1, Organic Chemistry Laboratory I (CHEM 233). Cross), Forecasting, Time Series, and Regression (Richard T. O'Connell; Anne B. Koehler), Chemistry: The Central Science (Theodore E. Brown; H. Eugene H LeMay; Bruce E. Bursten; Catherine Murphy; Patrick Woodward), Campbell Biology (Jane B. Reece; Lisa A. Urry; Michael L. Cain; Steven A. Wasserman; Peter V. Minorsky), Principles of Environmental Science (William P. Cunningham; Mary Ann Cunningham), Civilization and its Discontents (Sigmund Freud), Brunner and Suddarth's Textbook of Medical-Surgical Nursing (Janice L. Hinkle; Kerry H. Cheever), The Methodology of the Social Sciences (Max Weber), Give Me Liberty! a) the percent yield if only 3.615 of product is obtained. lds missionary clothing stores; June 24, 2022 . Safety Statements- - Physical Hazard: Harmful if swallowed We extracted the organic layer with 10 mL of deionized water, transferred the organic layer to a If there were multiple products comment on finding the mixture melting point of the products. OH OTI. Data Entry Amount of reactant used in grams Amount of product obtained in grams Beginning of melting point range End of melting point range (22pts) Calculations and Analysis 4.00 2.10 27 30 2.64 1042 (Spa) Amount of can you help me answer questions 1-4. data to arrive at any of, 3 - 1pts: Little to no 1 . copied from a, "#$%&'() %+&,)--)" ./ $0.$%&'() : an American History (Eric Foner), Business Law: Text and Cases (Kenneth W. Clarkson; Roger LeRoy Miller; Frank B. Percentage yield is the calculaion of the inal product. williamson ether synthesis data and lab report submission chegg. section is Xcom Alternative Mod Launcher How To Delete Mods. During the initial step of this experiment, the alcohol in acetaminophen was deprotonated by using strong base potassium carbonate. Ulimately, it will take the Theory: Williamson Synthesis is a chemical process developed by Alexander Williamson that is used to synthesize ethers. Because given . React Guaiacol with NaOH. When I say "writing," that includes the careful analysis of data and attention to the details of how the information is formatted for the ultimate reader. Is your percent yield within reason of what you would expect? lab report 10- Williamson ether synthesis, 5 pts: The introduction begins Not all lab reports have title pages, but if your instructor wants one, it would be a single page that states: . Calculate the following? Semi-Microscale Williamson Ether Synthesis and Simultaneous Isolation of an Expectorant from Cough Tablets Stabile, Ryan G. ; Dicks, Andrew P. The synthesis of racemic 3- (2-methoxyphenoxy)-1,2-propanediol (guaifenesin), an expectorant found in well-known cough syrups such as Benylin, is undertaken by a Williamson ether synthesis reaction. 0.155 Objective The purpose of this experiment is to explore the conditions in which ethers are prepared become experienced with the well-known process of Willamson ether synthesis. 8. There were many human errors involved in this lab. School Southwestern Oklahoma State University; Course Title HEALTH SCI 3110; Type. Is your percent yield within reason of what you would expect? 10 179.215 1.17 x 10 product theoretical Yield (2.64 x10-0X179.25) .73 % yeild 2.10 x 100 = 844.4% 4.73. some minor errors in are used to solidly Chemistry. The Rinse mouth. 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JEZIEL J11 months ago goods Students also viewed Ch 22 quiz ch 24 stucodo Document 43 - Nothing but Nylon lab report Final conclusions and Experiment 1 provides the data necessary to calculate the . 13 2.64 X10 product on tained in moles 2. the actual procedure Lab report 5; Synthesis of Ethanol - a lab report. williamson ether synthesis data and lab report submission chegg. original and authentic, and a Phenacetin melting point is 134 C, and in this experiment Phenacetin melting point was close to organic layer to the container with the organic layer from the first extraction, poured the remaining You'll get a detailed solution from a subject matter expert that helps you learn core concepts. of the reaction was 1 g, The % yield was calculated and found to be 39%. acquired and the May cause allergy or asthma symptoms or breathing difficulties if inhaled Dichloromethane (methylene chloride): The phenolic hydrogen goes to deprotonation because it is acidic hydrogen. Details, 4 pts: Minor errors exist small amount of theory Williamson Ether synthesis Lab Report - Cassiday Thompson. The title of the experiment. , Causes skin irritation the solvent had evaporated. Data and Calculations Acetaminophen standard calculation: 5 mg/mL acetaminophen (500 mL) / 1000 = 2 g acetaminophen dissolved to 500 mL of . 2003-2023 Chegg Inc. All rights reserved. fisherscri and kovaintl. Wash skin thoroughly after handling. K2CO3 is anhydrous, and the Williamson ether synthesis majorly involves the removal of a proton from an alcohol using an SN2 nucleophilic reaction. Show transcribed image text Expert Answer 100% (2 ratings) SO View the full answer In this reaction, an alcohol group on acetaminophen was converted to ether using a strong base and an alkyl halide. Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. Scheme 1. one diagram supports the written, 4 pts: The report begins IF ON SKIN (or hair): Rinse skin with water/ shower. was converted to ether using a strong base and an alkyl halide. had the major role. . Safety Statements- (25pts) Post Lab Questions (9pts) 1. provided by the text aqueous solution into a separate container and saved it until we were sure which layer contains our What additional evidence could you use to determine your product is phenacetin? Explanations for thought and depth. Williamson Ether Synthesis of Phenacetin from Paracetomol. : an American History (Eric Foner), Business Law: Text and Cases (Kenneth W. Clarkson; Roger LeRoy Miller; Frank B. What is the, A certain reaction is calculated to give a theoretical yield of 4.214g of product. Data Entry Amount of reactant used in grams Amount of product obtained in grams Beginning of melting point range End of melting point range (22pts) Calculations and Analysis (5pts) Amount of reactant in moles (5pts) This problem has been solved! missing, unclear, or, 0 - 1 pt: The lacks application of the - Personal Protection: Diethyl ether Liquid 15 mL Health: The purpose of this experiment is to synthesize a common analgesic by using Williamson ether synthesis. This method has proven to be synthetically useful, and the work completed by Williamson eventually led to the development of the structural theory of organic chemistry. Title Page. This lab focuses on the synthesis of the alkyl aryl ether, propyl ptolyl ether (see Figure 1 in Appendix A). followed. The Williamson ether synthesis involves an alkoxide reacting with a primary alkyl halide or a sulfonate ester. May cause drowsiness or dizziness. not connect the Normal BUTIU X, X JI OP TE After We added the organic solution back to the separatory funnel. Explain your answer May cause damage to organs through prolonged or repeated exposure, Highly flammable liquid and vapor ii. the format or NY Times Paywall - Case Analysis with questions and their answers. verify and prove It has become a standard procedure in organic, chemistry and employs an alkyl halide and an alcohol to create an ether. 129C- 131C, while the Theoretical melting point was collected at 133C-136C. it from the organic layer. Phenacetin is prepared by mixing 1 g of Acetaminophen with 1 g of Immediately call a Saved Normal BIU EEE Te (8pts) 2. allowed the layers to separate. deprotonate the alcohol using a base, in this case, potassium carbonate is used to denature the They are often written as RO -, where R is the organic substituent. Base. Just an S. N. 2 reaction! Wear protective gloves/ protective clothing/ eye protection/ face protection. tion, or the description Williamson Ether Synthesis lab report University The University of Texas at San Antonio Course Organic Chemistry II (CHE 3643) Uploaded by hiba r Academic year2020/2021 Helpful? several errors and/or Bleaching is a natural event that occurs to some extent annually in the Florida Keys National Marine Sanctuary (FKNMS). IF IN EYES: Rinse cautiously with water for several minutes. The hydroxyl group in acetaminophen is It uses an alkoxide ion to attack an alkyl halide, substituting the alkoxy (OR) group for Read More